Tackling CPE in Australia…

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Let’s talk about a serious health issue that’s affecting people around the world – the spread of carbapenemase-producing Enterobacterales (CPE). These little troublemakers are causing quite a stir in healthcare systems everywhere, and Australia is no exception. But fear not, there are ways to tackle this problem and minimize the risks.

Why should you care? Well, effective antibiotics are like the unsung heroes of modern medicine. They keep us safe during surgeries, cancer treatments, and childbirth. But here’s the catch: some bacteria, like CPE, are becoming resistant to antibiotics, making them a real threat. These sneaky bugs are part of the Enterobacterales family, and they can go from harmless gut-dwellers to life-threatening invaders.

CPE is born when these bacteria acquire genes that encode carbapenemase enzymes. These enzymes give them superpowers to break down powerful antibiotics, making treatment more challenging. What’s worse, CPE can spread quickly within and between bacterial populations, becoming multidrug-resistant monsters. Sometimes, they become pan-resistant, meaning no antibiotics can touch them.

The problem isn’t just in the hospitals – CPE can hitch a ride in your gut without you even knowing. Carriers can spread it to others through contact or contaminated surfaces, leading to infections in about 10-30% of carriers.

The impact isn’t just medical; it’s financial too. CPE outbreaks can cost healthcare systems millions. In Australia, individuals with asymptomatic CPE colonization end up with much higher healthcare costs. The WHO predicts billions in economic costs and millions of deaths due to antimicrobial resistance in the Western Pacific region.

Surveillance is vital. In 2022, there was a nearly 38% increase in CPE cases in Australia, and they affect all age groups. Hospitals bear the brunt, but CPE is also showing up in aged care and the community.

To fight this, we need a coordinated national response. Currently, CPE isn’t notifiable everywhere, leading to underestimation of the problem. We lack comprehensive data on CPE infections, making it hard to understand its spread.

Here’s the good news: Australia is taking steps to establish an Australian Centre for Disease Control in 2023. This body could lead a nationwide effort to tackle CPE systematically and effectively.

So, let’s work together to keep CPE in check and ensure a healthier and safer Australia for everyone. It’s an opportunity we can’t afford to miss.

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